Regent All Inclusive Mediterranean Cruises

History, Architecture & Stunning Beauty

Explore one of the world's richest centers of cultural history, architecture, and natural beauty: the Mediterranean. When you take an all-inclusive luxury cruise of the Mediterranean with Regent Cruise Destinations, you can expect to see everything the region has to offer.

Discover ancient worlds and cultural springs of wonder and beauty. Savor the fresh catch of the day with a pristinely aged vintage as you experience each colorful coast, from the stunning and enchanting Amalfi to the captivating history of Ephesus.

In Rome, relive epic gladiator battles in the iconic Colosseum, stand at the crossroads of the world's three great religions in Jerusalem's Old Town, and gaze across Athens from the magnificent Acropolis, where the seeds of democracy were planted over two centuries ago.

When you travel the Mediterranean with Regent Cruise Destinations, you'll sail to hidden coves for adventures less discovered as well as cosmopolitan cities with the world's most famous sights.

Featured Offers & Promotions
 Upgrade Your Horizon - Free Suite Upgrade 
Enjoy a free 2-Category Suite Upgrade when you book a select cruise sailing through June 2025. With 50% reduced deposits and 20% savings on select 2023 cruises.
Offer ends 3/31/2023.
 Up to $500 Onboard Credit 
Choose from 2021-2023 Sailings
Enjoy complimentary onboard credit of up to $500 per stateroom on select Regent Seven Seas Cruises voyages. Exclusively from Regent Cruise Destinations.
 Free Extended Land Programs 
FREE Pre or Post-Cruise Land Programs featuring a Dune Dinner Safari in Abu Dhabi, Shanghai & The Great Wall of China, Rome & the Vatican Museums, Wine Tasting in New Zealand and more!
 Virtuoso Voyages 
EXCLUSIVE AMENITIES!
With Virtuoso Voyages, enjoy a private welcome reception and onboard host - plus your choice of a private shore event, personalized experience credit toward exclusive Vi...
CruisesShip Sort by ShipDate Sort by SaildateFare FromSavings
7-Nights from Lisbon to Barcelona Cruise New OfferingSeven Seas MarinerOct 27, 2024$9,599
10-Nights from Athens to Barcelona Cruise  Seven Seas SplendorApr 29, 2023$12,099$13,350
9-Nights from Venice to Athens Cruise  Seven Seas VoyagerApr 29, 2023$11,799$13,600
10-Nights Roundtrip from London Cruise  Seven Seas SplendorMay 23, 2023$13,649$13,600
8-Nights from Istanbul to Athens Cruise  Seven Seas VoyagerMay 26, 2023$22,699$13,350
22-Nights from Barcelona to Istanbul Cruise  Seven Seas MarinerMay 30, 2023$22,799$13,350
10-Nights from Athens to Barcelona Cruise  Seven Seas VoyagerJun 15, 2023$12,799$13,350
10-Nights from Athens to Rome Cruise  Seven Seas MarinerJul 3, 2023$12,349$13,350
12-Nights from Lisbon to Rome Cruise  Seven Seas MarinerAug 2, 2023$14,149$13,600
10-Nights from Venice to Barcelona Cruise  Seven Seas MarinerAug 24, 2023$12,999$13,600
12-Nights from Amsterdam to Barcelona Cruise  Seven Seas NavigatorAug 28, 2023$11,299$13,350
14-Nights from Barcelona to New York Cruise  Seven Seas MarinerSep 3, 2023$10,249$13,500
12-Nights from Monte-Carlo to Athens Cruise  Seven Seas VoyagerSep 21, 2023$13,799$13,600
14-Nights from London to Barcelona Cruise  Seven Seas SplendorSep 24, 2023$16,299$13,350
12-Nights from Athens to Jerusalem Cruise  Seven Seas VoyagerOct 3, 2023$13,899$13,350
12-Nights from Barcelona to Venice Cruise  Seven Seas SplendorOct 8, 2023$14,549$13,350
10-Nights from Valletta to Venice Cruise  Seven Seas NavigatorOct 9, 2023$10,399$13,350
12-Nights from Athens to Istanbul Cruise  Seven Seas NavigatorOct 29, 2023$12,199$13,600
7-Nights from Athens to Rome Cruise  Seven Seas SplendorNov 6, 2023$9,699$13,600
7-Nights from Rome to Barcelona Cruise  Seven Seas SplendorNov 13, 2023$9,199$13,350
14-Nights from Miami to Barcelona Cruise Seven Seas VoyagerApr 5, 2023$8,099$13,400
12-Nights from Lisbon to Rome Cruise Seven Seas SplendorApr 9, 2023$12,599$13,250
10-Nights from Barcelona to Venice Cruise Seven Seas VoyagerApr 19, 2023$13,299$13,250
19-Nights from Barcelona to Athens Cruise Seven Seas VoyagerApr 19, 2023$21,799$13,000
8-Nights from Rome to Athens Cruise Seven Seas SplendorApr 21, 2023$11,849$13,000
24-Nights from Cape Town to Barcelona Cruise Seven Seas MarinerMay 6, 2023$19,749$13,000
14-Nights from Barcelona to London Cruise Seven Seas SplendorMay 9, 2023$16,199$13,000
12-Nights from Athens to Istanbul Cruise Seven Seas VoyagerMay 14, 2023$13,949$13,250
12-Nights from Barcelona to Rome Cruise Seven Seas MarinerMay 30, 2023$19,899$13,250
10-Nights from Rome to Istanbul Cruise Seven Seas MarinerJun 11, 2023$12,249$13,000
12-Nights from Istanbul to Athens Cruise Seven Seas MarinerJun 21, 2023$23,099$13,000
78-Nights from New York to Barcelona Cruise Seven Seas NavigatorJun 23, 2023$53,499$13,000
19-Nights from Barcelona to London Cruise Seven Seas VoyagerJun 25, 2023$20,099$13,000
7-Nights from Barcelona to Lisbon Cruise Seven Seas VoyagerJun 25, 2023$10,199$13,250
12-Nights from Lisbon to London Cruise Seven Seas VoyagerJul 2, 2023$14,949$13,000
10-Nights from Rome to Barcelona Cruise Seven Seas MarinerJul 13, 2023$12,749$13,000
20-Nights from Rome to Lisbon Cruise Seven Seas MarinerJul 13, 2023$21,799$13,000
10-Nights from Barcelona to Lisbon Cruise Seven Seas MarinerJul 23, 2023$13,149$13,250
10-Nights from Rome to Venice Cruise Seven Seas MarinerAug 14, 2023$12,999$13,250
20-Nights from Rome to Barcelona Cruise Seven Seas MarinerAug 14, 2023$21,699$13,000
24-Nights from Venice to New York Cruise Seven Seas MarinerAug 24, 2023$19,699$13,000
14-Nights from London to Monte-Carlo Cruise Seven Seas VoyagerSep 7, 2023$16,649$13,250
7-Nights from Barcelona to Lisbon Cruise Seven Seas NavigatorSep 22, 2023$14,299$13,000
10-Nights from Lisbon to Valletta Cruise Seven Seas NavigatorSep 29, 2023$10,699$13,000
22-Nights from Athens to Rome Cruise Seven Seas VoyagerOct 3, 2023$22,499$13,000
10-Nights from Jerusalem to Rome Cruise Seven Seas VoyagerOct 15, 2023$12,799$13,250
10-Nights from Venice to Athens Cruise Seven Seas NavigatorOct 19, 2023$10,599$13,250
10-Nights from Venice to Athens Cruise Seven Seas SplendorOct 20, 2023$12,799$13,000
24-Nights from Rome to Barcelona Cruise Seven Seas VoyagerOct 25, 2023$24,599$13,000
10-Nights from Rome to Istanbul Cruise Seven Seas VoyagerOct 25, 2023$12,649$13,000
14-Nights from Athens to Rome Cruise Seven Seas SplendorOct 30, 2023$14,599$13,000
7-Nights Roundtrip from Athens Cruise Seven Seas SplendorOct 30, 2023$9,249$13,000
14-Nights from Istanbul to Barcelona Cruise Seven Seas VoyagerNov 4, 2023$15,799$13,000
14-Nights from Athens to Barcelona Cruise Seven Seas SplendorNov 6, 2023$14,999$13,000
21-Nights from Istanbul to Dubai Cruise Seven Seas NavigatorNov 10, 2023$16,799$17,398
21-Nights from Rome to Miami Cruise Seven Seas SplendorNov 13, 2023$14,099$13,000
25-Nights from Barcelona to Cape Town Cruise Seven Seas VoyagerNov 18, 2023$18,199$17,398
14-Nights from Barcelona to Miami Cruise Seven Seas SplendorNov 20, 2023$8,399$13,000
14-Nights from Barcelona to Miami Cruise Seven Seas GrandeurNov 25, 2023$10,799$13,000
28-Nights from Buenos Aires to Lisbon Cruise Seven Seas VoyagerMar 9, 2024$18,499$17,398
18-Nights from Rio de Janeiro to Lisbon Cruise Seven Seas VoyagerMar 19, 2024$11,899$13,300
21-Nights from San Juan to Barcelona Cruise Seven Seas SplendorMar 24, 2024$13,099$13,000
14-Nights from Miami to Barcelona Cruise Seven Seas SplendorMar 31, 2024$8,899$13,300
10-Nights from Lisbon to Barcelona Cruise Seven Seas VoyagerApr 6, 2024$10,799$13,300
14-Nights from New York to Barcelona Cruise Seven Seas GrandeurApr 10, 2024$10,699$13,000
10-Nights from Barcelona to Rome Cruise Seven Seas SplendorApr 14, 2024$10,299$13,300
10-Nights from Barcelona to Athens Cruise Seven Seas VoyagerApr 16, 2024$11,299$13,300
7-Nights from Barcelona to Rome Cruise Seven Seas GrandeurApr 24, 2024$9,799$13,000
14-Nights Roundtrip from Barcelona Cruise Seven Seas GrandeurApr 24, 2024$16,099$13,000
19-Nights from Abu Dhabi to Athens Cruise Seven Seas NavigatorApr 25, 2024$14,299$17,398
12-Nights from Athens to Istanbul Cruise Seven Seas VoyagerApr 26, 2024$12,799$13,300
7-Nights from Rome to Athens Cruise Seven Seas SplendorApr 29, 2024$8,399$13,000
7-Nights from Rome to Barcelona Cruise Seven Seas GrandeurMay 1, 2024$9,299$13,000
10-Nights from Athens to Monte-Carlo Cruise Seven Seas SplendorMay 6, 2024$11,099$13,000
12-Nights from Barcelona to Venice Cruise Seven Seas GrandeurMay 8, 2024$13,749$13,000
7-Nights from Istanbul to Athens Cruise Seven Seas VoyagerMay 8, 2024$9,099$13,300
10-Nights from Athens to Trieste Cruise Seven Seas NavigatorMay 14, 2024$10,999$13,300
14-Nights from Athens to Valletta Cruise Seven Seas VoyagerMay 15, 2024$15,499$13,000
14-Nights from Monte-Carlo to London Cruise Seven Seas SplendorMay 16, 2024$16,099$13,000
10-Nights from Venice to Athens Cruise Seven Seas GrandeurMay 20, 2024$12,599$13,000
10-Nights from Trieste to Monte-Carlo Cruise Seven Seas NavigatorMay 24, 2024$10,299$13,000
10-Nights from Valletta to Barcelona Cruise Seven Seas VoyagerMay 29, 2024$12,149$13,300
12-Nights from Athens to Istanbul Cruise Seven Seas GrandeurMay 30, 2024$14,399$13,000
10-Nights Roundtrip from London Cruise Seven Seas SplendorMay 30, 2024$13,099$13,300
12-Nights from Monte-Carlo to Amsterdam Cruise Seven Seas NavigatorJun 3, 2024$12,099$13,300
10-Nights from Barcelona to Lisbon Cruise Seven Seas VoyagerJun 8, 2024$11,299$13,000
10-Nights from Istanbul to Athens Cruise Seven Seas GrandeurJun 11, 2024$12,649$13,000
10-Nights Roundtrip from Lisbon Cruise Seven Seas VoyagerJun 18, 2024$11,099$13,300
10-Nights from Athens to Rome Cruise Seven Seas GrandeurJun 21, 2024$11,799$13,000
14-Nights from Lisbon to Antwerp Cruise Seven Seas VoyagerJun 28, 2024$16,649$13,000
10-Nights from Rome to Monte-Carlo Cruise Seven Seas GrandeurJul 1, 2024$12,499$13,000
18-Nights from London to Copenhagen Cruise Seven Seas MarinerJul 5, 2024$18,999$13,300
10-Nights from Monte-Carlo to Barcelona Cruise Seven Seas GrandeurJul 11, 2024$12,599$13,300
10-Nights from Barcelona to Rome Cruise Seven Seas GrandeurJul 21, 2024$12,499$13,000
15-Nights from Belfast to Barcelona Cruise Seven Seas VoyagerJul 21, 2024$17,749$13,000
18-Nights from Reykjavik to London Cruise Seven Seas SplendorJul 25, 2024$20,299$13,300
14-Nights from Rome to Athens Cruise Seven Seas GrandeurJul 31, 2024$15,499$13,300
10-Nights from Barcelona to Athens Cruise Seven Seas VoyagerAug 5, 2024$12,749$13,000
12-Nights from Amsterdam to Barcelona Cruise Seven Seas MarinerAug 12, 2024$13,299$13,000
8-Nights Roundtrip from London Cruise Seven Seas SplendorAug 12, 2024$11,499$13,000
10-Nights from Athens to Barcelona Cruise Seven Seas GrandeurAug 14, 2024$11,799$13,000
7-Nights from Athens to Istanbul Cruise Seven Seas VoyagerAug 15, 2024$9,599$13,300
9-Nights from Istanbul to Jerusalem Cruise Seven Seas VoyagerAug 22, 2024$11,699$13,300
16-Nights from Barcelona to New York Cruise Seven Seas GrandeurAug 24, 2024$11,399$13,000
12-Nights from Barcelona to Rome Cruise Seven Seas MarinerAug 24, 2024$13,099$13,300
10-Nights Roundtrip from London Cruise Seven Seas NavigatorAug 25, 2024$10,299$13,000
15-Nights from Jerusalem to Lisbon Cruise Seven Seas VoyagerAug 31, 2024$15,399$13,000
14-Nights from London to Barcelona Cruise Seven Seas NavigatorSep 4, 2024$12,299$13,300
17-Nights from Rome to Monte-Carlo Cruise Seven Seas MarinerSep 5, 2024$17,999$13,300
10-Nights from Lisbon to Rome Cruise Seven Seas VoyagerSep 15, 2024$11,499$13,300
10-Nights from Barcelona to Rome Cruise Seven Seas NavigatorSep 18, 2024$10,799$13,000
10-Nights from Monte-Carlo to Lisbon Cruise Seven Seas MarinerSep 22, 2024$12,499$13,300
10-Nights from Rome to Trieste Cruise Seven Seas VoyagerSep 25, 2024$10,799$13,300
12-Nights from Rome to Athens Cruise Seven Seas NavigatorSep 28, 2024$11,599$13,300
10-Nights from Lisbon to Barcelona Cruise Seven Seas MarinerOct 2, 2024$12,099$13,000
15-Nights from London to Barcelona Cruise Seven Seas SplendorOct 4, 2024$16,799$13,000
10-Nights from Trieste to Athens Cruise Seven Seas VoyagerOct 5, 2024$11,799$13,300
12-Nights from Athens to Jerusalem Cruise Seven Seas NavigatorOct 10, 2024$12,599$13,000
12-Nights from Athens to Istanbul Cruise Seven Seas VoyagerOct 15, 2024$13,299$13,000
12-Nights from Barcelona to Athens Cruise Seven Seas SplendorOct 19, 2024$13,299$13,300
14-Nights from Jerusalem to Istanbul Cruise Seven Seas NavigatorOct 22, 2024$14,299$13,300
10-Nights from Istanbul to Barcelona Cruise Seven Seas VoyagerOct 27, 2024$9,999$13,000
12-Nights from Athens to Lisbon Cruise Seven Seas SplendorOct 31, 2024$11,299$13,000
14-Nights from Barcelona to Miami Cruise Seven Seas MarinerNov 3, 2024$8,299$13,300
10-Nights from Istanbul to Rome Cruise Seven Seas NavigatorNov 5, 2024$10,099$13,300
25-Nights from Barcelona to Cape Town Cruise Seven Seas VoyagerNov 6, 2024$19,399$13,000
7-Nights from Rome to Barcelona Cruise Seven Seas NavigatorNov 15, 2024$7,999$13,300
14-Nights from Barcelona to Miami Cruise Seven Seas NavigatorNov 22, 2024$7,299$13,000
14-Nights from Miami to Barcelona Cruise Seven Seas GrandeurMar 19, 2025$8,799$13,300
7-Nights from Lisbon to Barcelona Cruise Seven Seas NavigatorApr 16, 2025$8,699$13,000
18-Nights from Dubai to Athens Cruise Seven Seas VoyagerMay 16, 2025$17,599$13,000
67-Nights from Reykjavik to Athens CruiseSeven Seas SplendorAug 31, 2023$64,199
7-Nights from Trieste to Barcelona CruiseSeven Seas GrandeurNov 18, 2023$7,499
132-Nights Roundtrip from Miami CruiseSeven Seas MarinerJan 6, 2024$98,299
21-Nights from Abu Dhabi to Rome CruiseSeven Seas MarinerApr 8, 2024$18,899
18-Nights from Rome to Miami CruiseSeven Seas MarinerApr 29, 2024$14,599
83-Nights from New York to Barcelona CruiseSeven Seas MarinerJun 2, 2024$65,499
79-Nights Roundtrip from Lisbon CruiseSeven Seas VoyagerJun 28, 2024$67,749
10-Nights from Rome to Lisbon CruiseSeven Seas MarinerOct 17, 2024$11,699
70-Nights from Auckland to Athens CruiseSeven Seas VoyagerMar 25, 2025$51,799
Fares are per person in US dollars, based on double occupancy. Savings, Onboard Credits and other amenity values are quoted per stateroom/suite. All prices, discounts and special offers are capacity controlled and subject to change without notice. Not all special offers available in all categories and sailings. Availability and pricing is not guaranteed until booking and deposit received.