Regent All Inclusive South America Cruises

A Symphony for the Senses

When you take an all-inclusive voyage to South America with Regent Cruise Destinations, you'll experience the vibrant life that carries across the continent - from Rio to Lima.

Tap into the passion and spirit of Buenos Aires as you dance the tango, and taste the history and culture of Peru as you learn to prepare pre-Columbian dishes in Lima. Enjoy a symphony for the senses in the flavors of Chilean bean stew and the dark fruit and spice aromas of Uruguayan red wines. Kayak across a tranquil lake in Patagonia and watch for playful pink dolphins and giant water lilies as you cruise the mighty Amazon River.

On an all-inclusive Regent cruise to South America, spacious suites and exquisite cuisine are a given as are dynamic and diverse cruise itineraries and free unlimited shore excursions.

Featured Offers & Promotions
 Invite Guests and Earn Shipboard Credit 
Share your journey with friends and family and earn up to $3,000 shipboard and future cruise credit.
Offer ends September 30, 2023.
 Free Extended Land Programs 
FREE Pre or Post-Cruise Land Programs featuring a Dune Dinner Safari in Abu Dhabi, Rome & the Vatican Museums, Wine Tasting in New Zealand and much more!
 Virtuoso Voyages 
EXCLUSIVE AMENITIES!
With Virtuoso Voyages, enjoy a private welcome reception and onboard host - plus your choice of a private shore event, personalized experience credit toward exclusive Vi...
CruisesShip Sort by ShipDate Sort by SaildateFare FromSavings
21-Nights from Lima to Buenos Aires Cruise  Seven Seas SplendorDec 20, 2023$18,849$3,350
12-Nights from Buenos Aires to Rio de Janeiro Cruise  Seven Seas SplendorJan 10, 2024$13,599$3,350
24-Nights from Rio de Janeiro to Santiago Cruise  Seven Seas VoyagerJan 26, 2024$24,399$10,148
19-Nights from Santiago to Buenos Aires Cruise  Seven Seas VoyagerFeb 19, 2024$20,099$10,148
10-Nights from Buenos Aires to Rio de Janeiro Cruise  Seven Seas VoyagerMar 9, 2024$12,949$10,448
26-Nights from Buenos Aires to Lisbon Cruise  Seven Seas SplendorMar 3, 2025$19,199$7,148
24-Nights Roundtrip from Miami Cruise Seven Seas MarinerNov 17, 2024$13,149$250
16-Nights from Miami to Lima Cruise Seven Seas SplendorDec 4, 2023$11,799$3,000
67-Nights Roundtrip from Miami Cruise Seven Seas SplendorDec 4, 2023$68,999$3,000
25-Nights Roundtrip from Miami Cruise Seven Seas MarinerDec 12, 2023$14,499$3,000
16-Nights from Miami to Los Angeles Cruise Seven Seas GrandeurDec 21, 2023$13,049$3,000
132-Nights Roundtrip from Miami Cruise Seven Seas MarinerJan 6, 2024$96,299$3,000
17-Nights from Miami to San Francisco Cruise Seven Seas MarinerJan 7, 2024$15,799$3,000
16-Nights from Los Angeles to Miami Cruise Seven Seas GrandeurJan 8, 2024$11,999$3,000
30-Nights from Buenos Aires to Miami Cruise Seven Seas SplendorJan 10, 2024$23,799$3,000
14-Nights from Cape Town to Rio de Janeiro Cruise Seven Seas VoyagerJan 12, 2024$13,999$10,098
18-Nights from Rio de Janeiro to Miami Cruise Seven Seas SplendorJan 22, 2024$13,599$3,300
7-Nights from Rio de Janeiro to Buenos Aires Cruise Seven Seas VoyagerJan 26, 2024$10,599$3,000
17-Nights from Buenos Aires to Santiago Cruise Seven Seas VoyagerFeb 2, 2024$19,299$3,000
28-Nights from Buenos Aires to Lisbon Cruise Seven Seas VoyagerMar 9, 2024$19,999$9,798
18-Nights from Rio de Janeiro to Lisbon Cruise Seven Seas VoyagerMar 19, 2024$12,399$3,300
14-Nights from Cape Town to Rio de Janeiro Cruise Seven Seas SplendorJan 5, 2025$13,949$7,098
38-Nights from Cape Town to Santiago Cruise Seven Seas SplendorJan 5, 2025$30,899$6,798
24-Nights from Rio de Janeiro to Santiago Cruise Seven Seas SplendorJan 19, 2025$24,199$7,098
19-Nights from Santiago to Buenos Aires Cruise Seven Seas SplendorFeb 12, 2025$20,349$6,798
10-Nights from Buenos Aires to Rio de Janeiro Cruise Seven Seas SplendorMar 3, 2025$13,849$7,098
16-Nights from Rio de Janeiro to Lisbon Cruise Seven Seas SplendorMar 13, 2025$11,999$7,098
30-Nights from Miami to Rio de Janeiro Cruise Seven Seas SplendorNov 17, 2025$18,499$6,798
14-Nights from Bridgetown to Rio de Janeiro Cruise Seven Seas SplendorDec 3, 2025$12,599$6,798
11-Nights from Rio de Janeiro to Buenos Aires Cruise Seven Seas SplendorDec 17, 2025$14,399$6,798
17-Nights Roundtrip from Buenos Aires Cruise Seven Seas SplendorDec 28, 2025$19,899$6,798
18-Nights from Buenos Aires to Santiago Cruise Seven Seas SplendorJan 14, 2026$21,499$6,798
16-Nights from Santiago to Buenos Aires Cruise Seven Seas SplendorFeb 1, 2026$18,799$6,798
24-Nights from Buenos Aires to Miami Cruise Seven Seas SplendorFeb 17, 2026$18,399$6,798
16-Nights from Miami to Los Angeles CruiseSeven Seas GrandeurDec 13, 2024$10,699
150-Nights from Miami to San Francisco CruiseSeven Seas MarinerJan 7, 2025$95,999
168-Nights Roundtrip from Miami CruiseSeven Seas MarinerJan 7, 2025$107,299
16-Nights from Los Angeles to Miami CruiseSeven Seas GrandeurJan 8, 2025$10,999
17-Nights from Miami to Rio de Janeiro CruiseSeven Seas MarinerJan 8, 2025$15,299
22-Nights from Rio de Janeiro to Santiago CruiseSeven Seas MarinerJan 25, 2025$23,099
18-Nights from Santiago to Papeete CruiseSeven Seas MarinerFeb 16, 2025$20,299
25-Nights Roundtrip from Miami CruiseSeven Seas NavigatorFeb 24, 2025$12,099
18-Nights from San Francisco to Miami CruiseSeven Seas MarinerJun 6, 2025$13,899
16-Nights from Miami to Bridgetown CruiseSeven Seas SplendorNov 17, 2025$9,499
12-Nights from Miami to Panama City CruiseSeven Seas GrandeurJan 3, 2026$8,299
22-Nights from Miami to Los Angeles CruiseSeven Seas GrandeurJan 3, 2026$13,699
154-Nights Roundtrip from Miami CruiseSeven Seas MarinerJan 10, 2026$97,599
21-Nights from Miami to Honolulu CruiseSeven Seas MarinerJan 11, 2026$16,499
35-Nights from Miami to Papeete CruiseSeven Seas MarinerJan 11, 2026$26,799
16-Nights from Los Angeles to Miami CruiseSeven Seas GrandeurJan 25, 2026$10,499
53-Nights from Singapore to Lisbon CruiseSeven Seas MarinerApr 9, 2026$39,699
23-Nights from Cape Town to Lisbon CruiseSeven Seas MarinerMay 9, 2026$19,499
35-Nights from Cape Town to Miami CruiseSeven Seas MarinerMay 9, 2026$24,599
Fares are per person in US dollars, based on double occupancy. Savings, Onboard Credits and other amenity values are quoted per stateroom/suite. All prices, discounts and special offers are capacity controlled and subject to change without notice. Not all special offers available in all categories and sailings. Availability and pricing is not guaranteed until booking and deposit received.