Regent All Inclusive South America Cruises

A Symphony for the Senses

When you take an all-inclusive voyage to South America with Regent Cruise Destinations, you'll experience the vibrant life that carries across the continent - from Rio to Lima.

Tap into the passion and spirit of Buenos Aires as you dance the tango, and taste the history and culture of Peru as you learn to prepare pre-Columbian dishes in Lima. Enjoy a symphony for the senses in the flavors of Chilean bean stew and the dark fruit and spice aromas of Uruguayan red wines. Kayak across a tranquil lake in Patagonia and watch for playful pink dolphins and giant water lilies as you cruise the mighty Amazon River.

On an all-inclusive Regent cruise to South America, spacious suites and exquisite cuisine are a given as are dynamic and diverse cruise itineraries and free unlimited shore excursions.

Featured Offers & Promotions
 Free Pre- and Post-Cruise Explorations 
Free Explorations
Book a select 2022-2023 South America cruise and enjoy FREE pre- and post-cruise extended land programs.
Offer ends Sep 30, 2021.
 Unique Spotlight Voyages from Regent 
Unique Spotlight Voyages
Complimentary onshore and onboard experiences tailored to a spotlighted theme of a particular cruise. Savor a new cuisine, interact with awarded filmmakers, or expe...
 Up to $500 Onboard Credit 
Choose from 2021-2023 Sailings
Enjoy complimentary onboard credit of up to $500 per stateroom on select Regent Seven Seas Cruises voyages. Exclusively from Regent Cruise Destinations.
 Free Extended Land Programs 
FREE Pre or Post-Cruise Land Programs featuring a Dune Dinner Safari in Abu Dhabi, Shanghai & The Great Wall of China, Rome & the Vatican Museums, Wine Tasting in New Zealand and more!
 Virtuoso Voyages 
EXCLUSIVE AMENITIES!
With Virtuoso Voyages, enjoy a private welcome reception and onboard host - plus your choice of a private shore event, personalized experience credit toward exclusive Vi...
CruisesShip Sort by ShipDate Sort by SaildateFare FromSavings
16-Nights from Miami to Los Angeles Cruise New OfferingSeven Seas GrandeurDec 21, 2023$9,399
16-Nights from Los Angeles to Miami Cruise New OfferingSeven Seas GrandeurJan 8, 2024$9,199
12-Nights from Amsterdam to Lisbon Cruise  Seven Seas VoyagerSep 2, 2022$12,449$750
21-Nights from Lima to Buenos Aires Cruise  Seven Seas MarinerNov 19, 2022$30,999$3,750
10-Nights from Buenos Aires to Rio de Janeiro Cruise  Seven Seas MarinerDec 10, 2022$10,699$3,350
143-Nights from Miami to Barcelona Cruise  Seven Seas MarinerJan 7, 2023$86,699$1,800
10-Nights from Rio de Janeiro to Buenos Aires Cruise  Seven Seas VoyagerJan 19, 2023$12,199$7,748
16-Nights from Santiago to Buenos Aires Cruise  Seven Seas VoyagerFeb 17, 2023$16,199$7,748
10-Nights from Buenos Aires to Rio de Janeiro Cruise  Seven Seas VoyagerMar 5, 2023$11,799$7,748
12-Nights from San Juan to Cartagena Cruise Seven Seas NavigatorJan 13, 2022$7,699$250
16-Nights from Los Angeles to Miami Cruise Seven Seas SplendorJan 5, 2023$9,499$250
11-Nights from Cartagena to Bridgetown Cruise Seven Seas NavigatorJan 25, 2022$10,999$400
16-Nights from Los Angeles to Lima Cruise Seven Seas MarinerNov 3, 2022$11,599$3,000
24-Nights from Lisbon to Cape Town Cruise Seven Seas VoyagerNov 12, 2022$16,299$4,798
18-Nights from Rio de Janeiro to Miami Cruise Seven Seas MarinerDec 20, 2022$12,499$3,000
16-Nights from Miami to Los Angeles Cruise Seven Seas SplendorDec 20, 2022$16,299$400
14-Nights from Cape Town to Rio de Janeiro Cruise Seven Seas VoyagerJan 5, 2023$12,749$7,798
24-Nights from Cape Town to Buenos Aires Cruise Seven Seas VoyagerJan 5, 2023$18,699$4,398
29-Nights from Rio de Janeiro to Santiago Cruise Seven Seas VoyagerJan 19, 2023$24,899$4,398
19-Nights from Buenos Aires to Santiago Cruise Seven Seas VoyagerJan 29, 2023$18,599$4,398
26-Nights from Santiago to Rio de Janeiro Cruise Seven Seas VoyagerFeb 17, 2023$22,899$4,798
21-Nights from Rio de Janeiro to Miami Cruise Seven Seas VoyagerMar 15, 2023$14,849$7,398
14-Nights from Cape Town to Rio de Janeiro Cruise Seven Seas VoyagerJan 12, 2024$12,449$250
18-Nights from Rio de Janeiro to Miami Cruise Seven Seas SplendorJan 22, 2024$11,999$250
10-Nights from Buenos Aires to Rio de Janeiro Cruise Seven Seas VoyagerMar 9, 2024$11,299$250
18-Nights from Rio de Janeiro to Lisbon Cruise Seven Seas VoyagerMar 19, 2024$9,799$250
24-Nights Roundtrip from Miami CruiseSeven Seas ExplorerNov 15, 2021$11,899
8-Nights from Colon to Bridgetown CruiseSeven Seas ExplorerNov 23, 2021$5,099
18-Nights from Miami to San Francisco CruiseSeven Seas MarinerDec 18, 2021$15,299
16-Nights from Miami to San Diego CruiseSeven Seas ExplorerJan 3, 2022$9,399
120-Nights Roundtrip from San Francisco CruiseSeven Seas MarinerJan 5, 2022$78,299
18-Nights from San Francisco to Miami CruiseSeven Seas MarinerJan 5, 2022$10,999
30-Nights from Miami to Bridgetown CruiseSeven Seas NavigatorJan 6, 2022$19,999
16-Nights from San Diego to Miami CruiseSeven Seas ExplorerJan 19, 2022$10,199
65-Nights from Los Angeles to Miami CruiseSeven Seas MarinerNov 3, 2022$40,899
28-Nights from Buenos Aires to Miami CruiseSeven Seas MarinerDec 10, 2022$19,199
23-Nights from Miami to Los Angeles CruiseSeven Seas SplendorDec 13, 2022$23,699
24-Nights Roundtrip from Miami CruiseSeven Seas NavigatorMar 28, 2023$10,149
25-Nights from Barcelona to Cape Town CruiseSeven Seas VoyagerNov 18, 2023$17,699
16-Nights from Miami to Lima CruiseSeven Seas SplendorDec 4, 2023$10,799
67-Nights Roundtrip from Miami CruiseSeven Seas SplendorDec 4, 2023$39,299
25-Nights Roundtrip from Miami CruiseSeven Seas MarinerDec 12, 2023$12,249
21-Nights from Lima to Buenos Aires CruiseSeven Seas SplendorDec 20, 2023$17,299
132-Nights Roundtrip from Miami CruiseSeven Seas MarinerJan 6, 2024$78,799
12-Nights from Buenos Aires to Rio de Janeiro CruiseSeven Seas SplendorJan 10, 2024$11,499
30-Nights from Buenos Aires to Miami CruiseSeven Seas SplendorJan 10, 2024$18,199
24-Nights from Rio de Janeiro to Santiago CruiseSeven Seas VoyagerJan 26, 2024$21,799
19-Nights from Santiago to Buenos Aires CruiseSeven Seas VoyagerFeb 19, 2024$18,299
28-Nights from Buenos Aires to Lisbon CruiseSeven Seas VoyagerMar 9, 2024$17,499
Fares are per person in US dollars, based on double occupancy. Savings, Onboard Credits and other amenity values are quoted per stateroom/suite. All prices, discounts and special offers are capacity controlled and subject to change without notice. Not all special offers available in all categories and sailings. Availability and pricing is not guaranteed until booking and deposit received.