Regent All Inclusive South America Cruises

A Symphony for the Senses

When you take an all-inclusive voyage to South America with Regent Cruise Destinations, you'll experience the vibrant life that carries across the continent - from Rio to Lima.

Tap into the passion and spirit of Buenos Aires as you dance the tango, and taste the history and culture of Peru as you learn to prepare pre-Columbian dishes in Lima. Enjoy a symphony for the senses in the flavors of Chilean bean stew and the dark fruit and spice aromas of Uruguayan red wines. Kayak across a tranquil lake in Patagonia and watch for playful pink dolphins and giant water lilies as you cruise the mighty Amazon River.

On an all-inclusive Regent cruise to South America, spacious suites and exquisite cuisine are a given as are dynamic and diverse cruise itineraries and free unlimited shore excursions.

Featured Offers & Promotions
 Unique Spotlight Voyages from Regent 
Unique Spotlight Voyages
Complimentary onshore and onboard experiences tailored to a spotlighted theme of a particular cruise. Savor a new cuisine, interact with awarded filmmakers, or expe...
 Up to $500 Onboard Credit 
Choose from 2021-2023 Sailings
Enjoy complimentary onboard credit of up to $500 per stateroom on select Regent Seven Seas Cruises voyages. Exclusively from Regent Cruise Destinations.
 Free Extended Land Programs 
FREE Pre or Post-Cruise Land Programs featuring a Dune Dinner Safari in Abu Dhabi, Shanghai & The Great Wall of China, Rome & the Vatican Museums, Wine Tasting in New Zealand and more!
 Virtuoso Voyages 
EXCLUSIVE AMENITIES!
With Virtuoso Voyages, enjoy a private welcome reception and onboard host - plus your choice of a private shore event, personalized experience credit toward exclusive Vi...
CruisesShip Sort by ShipDate Sort by SaildateFare FromSavings
18-Nights from Miami to Rio de Janeiro Cruise  Seven Seas NavigatorNov 5, 2021$9,299$800
14-Nights from Cape Town to Rio de Janeiro Cruise  Seven Seas VoyagerDec 22, 2021$12,399$5,148
10-Nights from Rio de Janeiro to Buenos Aires Cruise  Seven Seas VoyagerJan 5, 2022$12,099$4,748
16-Nights from Buenos Aires to Santiago Cruise  Seven Seas VoyagerJan 15, 2022$35,999$4,748
12-Nights from Amsterdam to Lisbon Cruise  Seven Seas VoyagerSep 2, 2022$12,449$750
21-Nights from Lima to Buenos Aires Cruise  Seven Seas MarinerNov 19, 2022$23,999$750
143-Nights from Miami to Barcelona Cruise  Seven Seas MarinerJan 7, 2023$86,699$1,800
10-Nights from Rio de Janeiro to Buenos Aires Cruise  Seven Seas VoyagerJan 19, 2023$11,699$4,748
16-Nights from Santiago to Buenos Aires Cruise  Seven Seas VoyagerFeb 17, 2023$16,199$4,748
10-Nights from Buenos Aires to Rio de Janeiro Cruise  Seven Seas VoyagerMar 5, 2023$11,699$4,748
12-Nights from San Juan to Cartagena Cruise Seven Seas NavigatorJan 13, 2022$8,999$250
10-Nights from Buenos Aires to Rio de Janeiro Cruise Seven Seas MarinerDec 10, 2022$10,599$350
16-Nights from Los Angeles to Miami Cruise Seven Seas SplendorJan 5, 2023$9,299$250
34-Nights from Buenos Aires to Miami Cruise Seven Seas NavigatorDec 3, 2021$26,599$400
26-Nights from Rio de Janeiro to Santiago Cruise Seven Seas VoyagerJan 5, 2022$22,599$4,398
11-Nights from Cartagena to Bridgetown Cruise Seven Seas NavigatorJan 25, 2022$5,999$400
19-Nights from Santiago to Buenos Aires Cruise Seven Seas VoyagerJan 31, 2022$25,999$4,798
29-Nights from Santiago to Rio de Janeiro Cruise Seven Seas VoyagerJan 31, 2022$24,399$4,398
10-Nights from Buenos Aires to Rio de Janeiro Cruise Seven Seas VoyagerFeb 19, 2022$26,499$4,398
31-Nights from Buenos Aires to Miami Cruise Seven Seas VoyagerFeb 19, 2022$60,799$4,398
21-Nights from Rio de Janeiro to Miami Cruise Seven Seas VoyagerMar 1, 2022$24,799$4,798
16-Nights from Los Angeles to Lima Cruise Seven Seas MarinerNov 3, 2022$11,099
24-Nights from Lisbon to Cape Town Cruise Seven Seas VoyagerNov 12, 2022$16,299$4,798
16-Nights from Miami to Los Angeles Cruise Seven Seas SplendorDec 20, 2022$23,799$400
14-Nights from Cape Town to Rio de Janeiro Cruise Seven Seas VoyagerJan 5, 2023$12,749$4,798
24-Nights from Cape Town to Buenos Aires Cruise Seven Seas VoyagerJan 5, 2023$18,499$4,398
29-Nights from Rio de Janeiro to Santiago Cruise Seven Seas VoyagerJan 19, 2023$24,699$4,398
19-Nights from Buenos Aires to Santiago Cruise Seven Seas VoyagerJan 29, 2023$18,499$4,398
26-Nights from Santiago to Rio de Janeiro Cruise Seven Seas VoyagerFeb 17, 2023$22,699$4,798
21-Nights from Rio de Janeiro to Miami Cruise Seven Seas VoyagerMar 15, 2023$14,749$4,398
28-Nights from Miami to Buenos Aires CruiseSeven Seas NavigatorNov 5, 2021$20,099
62-Nights Roundtrip from Miami Holiday CruiseSeven Seas NavigatorNov 5, 2021$41,399
10-Nights from Rio de Janeiro to Buenos Aires CruiseSeven Seas NavigatorNov 23, 2021$10,999
16-Nights from Buenos Aires to Santiago CruiseSeven Seas NavigatorDec 3, 2021$12,499
18-Nights from Miami to San Francisco CruiseSeven Seas MarinerDec 18, 2021$9,999
18-Nights from Santiago to Miami CruiseSeven Seas NavigatorDec 19, 2021$16,599
30-Nights from Miami to Bridgetown CruiseSeven Seas NavigatorJan 6, 2022$19,499
65-Nights from Los Angeles to Miami CruiseSeven Seas MarinerNov 3, 2022$40,499
28-Nights from Buenos Aires to Miami CruiseSeven Seas MarinerDec 10, 2022$18,999
23-Nights from Miami to Los Angeles CruiseSeven Seas SplendorDec 13, 2022$12,699
18-Nights from Rio de Janeiro to Miami CruiseSeven Seas MarinerDec 20, 2022$12,399
Fares are per person in US dollars, based on double occupancy. Savings, Onboard Credits and other amenity values are quoted per stateroom/suite. All prices, discounts and special offers are capacity controlled and subject to change without notice. Not all special offers available in all categories and sailings. Availability and pricing is not guaranteed until booking and deposit received.