Regent All Inclusive South America Cruises

A Symphony for the Senses

When you take an all-inclusive voyage to South America with Regent Cruise Destinations, you'll experience the vibrant life that carries across the continent - from Rio to Lima.

Tap into the passion and spirit of Buenos Aires as you dance the tango, and taste the history and culture of Peru as you learn to prepare pre-Columbian dishes in Lima. Enjoy a symphony for the senses in the flavors of Chilean bean stew and the dark fruit and spice aromas of Uruguayan red wines. Kayak across a tranquil lake in Patagonia and watch for playful pink dolphins and giant water lilies as you cruise the mighty Amazon River.

On an all-inclusive Regent cruise to South America, spacious suites and exquisite cuisine are a given as are dynamic and diverse cruise itineraries and free unlimited shore excursions.

Featured Offers & Promotions
 Gift of Travel - 10% Fare Savings 
Enjoy 10% fare savings on select 2022 Regent voyages to worldwide destinations.
Offer ends Dec 31, 2021.
 Unique Spotlight Voyages from Regent 
Unique Spotlight Voyages
Complimentary onshore and onboard experiences tailored to a spotlighted theme of a particular cruise. Savor a new cuisine, interact with awarded filmmakers, or expe...
 Up to $500 Onboard Credit 
Choose from 2021-2023 Sailings
Enjoy complimentary onboard credit of up to $500 per stateroom on select Regent Seven Seas Cruises voyages. Exclusively from Regent Cruise Destinations.
 Free Extended Land Programs 
FREE Pre or Post-Cruise Land Programs featuring a Dune Dinner Safari in Abu Dhabi, Shanghai & The Great Wall of China, Rome & the Vatican Museums, Wine Tasting in New Zealand and more!
 Virtuoso Voyages 
EXCLUSIVE AMENITIES!
With Virtuoso Voyages, enjoy a private welcome reception and onboard host - plus your choice of a private shore event, personalized experience credit toward exclusive Vi...
CruisesShip Sort by ShipDate Sort by SaildateFare FromSavings
12-Nights from Amsterdam to Lisbon Cruise  Seven Seas VoyagerSep 2, 2022$14,399$4,800
21-Nights from Lima to Buenos Aires Cruise  Seven Seas MarinerNov 19, 2022$24,999$750
10-Nights from Buenos Aires to Rio de Janeiro Cruise  Seven Seas MarinerDec 10, 2022$10,799$4,350
143-Nights from Miami to Barcelona Cruise  Seven Seas MarinerJan 7, 2023$86,699$1,800
10-Nights from Rio de Janeiro to Buenos Aires Cruise  Seven Seas VoyagerJan 19, 2023$12,299$4,748
16-Nights from Santiago to Buenos Aires Cruise  Seven Seas VoyagerFeb 17, 2023$23,299$4,748
10-Nights from Buenos Aires to Rio de Janeiro Cruise  Seven Seas VoyagerMar 5, 2023$11,899$4,748
10-Nights from Buenos Aires to Rio de Janeiro Cruise  Seven Seas VoyagerMar 9, 2024$11,299$600
16-Nights from Miami to San Diego Cruise Seven Seas ExplorerJan 3, 2022$9,999$350
12-Nights from San Juan to Cartagena Cruise Seven Seas NavigatorJan 13, 2022$8,099$250
16-Nights from San Diego to Miami Cruise Seven Seas ExplorerJan 19, 2022$10,199$350
16-Nights from Los Angeles to Miami Cruise Seven Seas SplendorJan 5, 2023$9,949$250
21-Nights from Lima to Buenos Aires Cruise Seven Seas SplendorDec 20, 2023$17,749$350
12-Nights from Buenos Aires to Rio de Janeiro Cruise Seven Seas SplendorJan 10, 2024$11,899$350
24-Nights from Rio de Janeiro to Santiago Cruise Seven Seas VoyagerJan 26, 2024$21,799$350
19-Nights from Santiago to Buenos Aires Cruise Seven Seas VoyagerFeb 19, 2024$18,299$350
11-Nights from Cartagena to Bridgetown Cruise Seven Seas NavigatorJan 25, 2022$10,999$400
16-Nights from Los Angeles to Lima Cruise Seven Seas MarinerNov 3, 2022$11,699
24-Nights from Lisbon to Cape Town Cruise Seven Seas VoyagerNov 12, 2022$16,299$4,798
18-Nights from Rio de Janeiro to Miami Cruise Seven Seas MarinerDec 20, 2022$12,199$4,000
16-Nights from Miami to Los Angeles Cruise Seven Seas SplendorDec 20, 2022$16,299$400
14-Nights from Cape Town to Rio de Janeiro Cruise Seven Seas VoyagerJan 5, 2023$12,749$4,798
24-Nights from Cape Town to Buenos Aires Cruise Seven Seas VoyagerJan 5, 2023$18,899$4,398
29-Nights from Rio de Janeiro to Santiago Cruise Seven Seas VoyagerJan 19, 2023$25,199$4,398
19-Nights from Buenos Aires to Santiago Cruise Seven Seas VoyagerJan 29, 2023$18,799$4,398
26-Nights from Santiago to Rio de Janeiro Cruise Seven Seas VoyagerFeb 17, 2023$23,099$4,798
21-Nights from Rio de Janeiro to Miami Cruise Seven Seas VoyagerMar 15, 2023$14,949$4,398
14-Nights from Cape Town to Rio de Janeiro Cruise Seven Seas VoyagerJan 12, 2024$12,449$250
18-Nights from Rio de Janeiro to Miami Cruise Seven Seas SplendorJan 22, 2024$12,399$250
18-Nights from Rio de Janeiro to Lisbon Cruise Seven Seas VoyagerMar 19, 2024$9,799$250
18-Nights from Miami to San Francisco CruiseSeven Seas MarinerDec 18, 2021$18,699
120-Nights Roundtrip from San Francisco CruiseSeven Seas MarinerJan 5, 2022$78,299
18-Nights from San Francisco to Miami CruiseSeven Seas MarinerJan 5, 2022$14,499
30-Nights from Miami to Bridgetown CruiseSeven Seas NavigatorJan 6, 2022$19,999
65-Nights from Los Angeles to Miami CruiseSeven Seas MarinerNov 3, 2022$41,299
28-Nights from Buenos Aires to Miami CruiseSeven Seas MarinerDec 10, 2022$19,399
23-Nights from Miami to Los Angeles CruiseSeven Seas SplendorDec 13, 2022$14,699
24-Nights Roundtrip from Miami CruiseSeven Seas NavigatorMar 28, 2023$10,149
25-Nights from Barcelona to Cape Town CruiseSeven Seas VoyagerNov 18, 2023$17,699
16-Nights from Miami to Lima CruiseSeven Seas SplendorDec 4, 2023$11,249
67-Nights Roundtrip from Miami CruiseSeven Seas SplendorDec 4, 2023$40,999
25-Nights Roundtrip from Miami CruiseSeven Seas MarinerDec 12, 2023$12,249
16-Nights from Miami to Los Angeles CruiseSeven Seas GrandeurDec 21, 2023$9,399
132-Nights Roundtrip from Miami CruiseSeven Seas MarinerJan 6, 2024$82,299
16-Nights from Los Angeles to Miami CruiseSeven Seas GrandeurJan 8, 2024$9,199
30-Nights from Buenos Aires to Miami CruiseSeven Seas SplendorJan 10, 2024$18,999
28-Nights from Buenos Aires to Lisbon CruiseSeven Seas VoyagerMar 9, 2024$17,499
Fares are per person in US dollars, based on double occupancy. Savings, Onboard Credits and other amenity values are quoted per stateroom/suite. All prices, discounts and special offers are capacity controlled and subject to change without notice. Not all special offers available in all categories and sailings. Availability and pricing is not guaranteed until booking and deposit received.