Regent All Inclusive South America Cruises

A Symphony for the Senses

When you take an all-inclusive voyage to South America with Regent Cruise Destinations, you'll experience the vibrant life that carries across the continent - from Rio to Lima.

Tap into the passion and spirit of Buenos Aires as you dance the tango, and taste the history and culture of Peru as you learn to prepare pre-Columbian dishes in Lima. Enjoy a symphony for the senses in the flavors of Chilean bean stew and the dark fruit and spice aromas of Uruguayan red wines. Kayak across a tranquil lake in Patagonia and watch for playful pink dolphins and giant water lilies as you cruise the mighty Amazon River.

On an all-inclusive Regent cruise to South America, spacious suites and exquisite cuisine are a given as are dynamic and diverse cruise itineraries and free unlimited shore excursions.

Featured Offers & Promotions
 Unique Spotlight Voyages from Regent 
Unique Spotlight Voyages
Complimentary onshore and onboard experiences tailored to a spotlighted theme of a particular cruise. Savor a new cuisine, interact with awarded filmmakers, or expe...
 Fare Savings on South America Cruises 
Enjoy 25% fare savings on select South America cruises departing in early 2023.
Offer ends December 4, 2022.
 Up to $500 Onboard Credit 
Choose from 2021-2023 Sailings
Enjoy complimentary onboard credit of up to $500 per stateroom on select Regent Seven Seas Cruises voyages. Exclusively from Regent Cruise Destinations.
 Free Extended Land Programs 
FREE Pre or Post-Cruise Land Programs featuring a Dune Dinner Safari in Abu Dhabi, Shanghai & The Great Wall of China, Rome & the Vatican Museums, Wine Tasting in New Zealand and more!
 Virtuoso Voyages 
EXCLUSIVE AMENITIES!
With Virtuoso Voyages, enjoy a private welcome reception and onboard host - plus your choice of a private shore event, personalized experience credit toward exclusive Vi...
CruisesShip Sort by ShipDate Sort by SaildateFare FromSavings
21-Nights from Lima to Buenos Aires Cruise  Seven Seas MarinerNov 19, 2022$30,999$750
143-Nights from Miami to Barcelona Cruise  Seven Seas MarinerJan 7, 2023$108,299$1,800
10-Nights from Rio de Janeiro to Buenos Aires Cruise  Seven Seas VoyagerJan 19, 2023$12,599$13,948
16-Nights from Santiago to Buenos Aires Cruise  Seven Seas VoyagerFeb 17, 2023$18,299$13,948
10-Nights from Buenos Aires to Rio de Janeiro Cruise  Seven Seas VoyagerMar 5, 2023$12,599$13,948
24-Nights from Rio de Janeiro to Santiago Cruise  Seven Seas VoyagerJan 26, 2024$22,899$4,748
19-Nights from Santiago to Buenos Aires Cruise  Seven Seas VoyagerFeb 19, 2024$19,199$4,748
10-Nights from Buenos Aires to Rio de Janeiro Cruise  Seven Seas VoyagerMar 9, 2024$12,149$4,998
10-Nights from Buenos Aires to Rio de Janeiro Cruise Seven Seas MarinerDec 10, 2022$11,499$350
16-Nights from Los Angeles to Miami Cruise Seven Seas SplendorJan 5, 2023$10,849$250
21-Nights from Lima to Buenos Aires Cruise Seven Seas SplendorDec 20, 2023$18,249$350
12-Nights from Buenos Aires to Rio de Janeiro Cruise Seven Seas SplendorJan 10, 2024$12,399$350
16-Nights from Los Angeles to Lima Cruise Seven Seas MarinerNov 3, 2022$12,099
25-Nights Roundtrip from Miami Cruise Seven Seas NavigatorNov 17, 2022$19,399$400
16-Nights from Miami to Los Angeles Cruise Seven Seas SplendorDec 20, 2022$16,299$400
14-Nights from Cape Town to Rio de Janeiro Cruise Seven Seas VoyagerJan 5, 2023$12,749$13,998
24-Nights from Cape Town to Buenos Aires Cruise Seven Seas VoyagerJan 5, 2023$19,599$4,398
29-Nights from Rio de Janeiro to Santiago Cruise Seven Seas VoyagerJan 19, 2023$27,199$4,398
19-Nights from Buenos Aires to Santiago Cruise Seven Seas VoyagerJan 29, 2023$20,299$4,398
26-Nights from Santiago to Rio de Janeiro Cruise Seven Seas VoyagerFeb 17, 2023$23,699$4,798
21-Nights from Rio de Janeiro to Miami Cruise Seven Seas VoyagerMar 15, 2023$15,249$13,598
14-Nights from Cape Town to Rio de Janeiro Cruise Seven Seas VoyagerJan 12, 2024$12,399$4,648
18-Nights from Rio de Janeiro to Miami Cruise Seven Seas SplendorJan 22, 2024$12,799$250
28-Nights from Buenos Aires to Lisbon Cruise Seven Seas VoyagerMar 9, 2024$18,299$4,398
18-Nights from Rio de Janeiro to Lisbon Cruise Seven Seas VoyagerMar 19, 2024$10,699$250
65-Nights from Los Angeles to Miami CruiseSeven Seas MarinerNov 3, 2022$42,599
28-Nights from Buenos Aires to Miami CruiseSeven Seas MarinerDec 10, 2022$19,999
23-Nights from Miami to Los Angeles CruiseSeven Seas SplendorDec 13, 2022$14,699
18-Nights from Rio de Janeiro to Miami CruiseSeven Seas MarinerDec 20, 2022$12,899
25-Nights from Miami to Papeete CruiseSeven Seas MarinerJan 8, 2023$22,399
24-Nights Roundtrip from Miami CruiseSeven Seas NavigatorMar 28, 2023$10,399
16-Nights from Miami to Lima CruiseSeven Seas SplendorDec 4, 2023$11,649
67-Nights Roundtrip from Miami CruiseSeven Seas SplendorDec 4, 2023$42,799
25-Nights Roundtrip from Miami CruiseSeven Seas MarinerDec 12, 2023$12,749
16-Nights from Miami to Los Angeles CruiseSeven Seas GrandeurDec 21, 2023$10,349
132-Nights Roundtrip from Miami CruiseSeven Seas MarinerJan 6, 2024$89,299
16-Nights from Los Angeles to Miami CruiseSeven Seas GrandeurJan 8, 2024$9,799
30-Nights from Buenos Aires to Miami CruiseSeven Seas SplendorJan 10, 2024$19,899
168-Nights Roundtrip from Miami CruiseSeven Seas MarinerJan 7, 2025$101,299
150-Nights from Miami to San Francisco CruiseSeven Seas MarinerJan 7, 2025$0
Fares are per person in US dollars, based on double occupancy. Savings, Onboard Credits and other amenity values are quoted per stateroom/suite. All prices, discounts and special offers are capacity controlled and subject to change without notice. Not all special offers available in all categories and sailings. Availability and pricing is not guaranteed until booking and deposit received.